Groundbreaking Initiative to Create Largest African Genome Database

A collective of scientists, spearheaded by Meharry Medical College in Nashville, Tennessee, alongside the Regeneron Genetics Center, pharmaceutical titans AstraZeneca, Novo Nordisk and Roche have unveiled a grand initiative in genetic research. The ambitious project seeks to source genetic material from an impressive half a million African individuals. The aspiration? To amass the world's largest database of African population genomic information.

Although 99% of two people's genomes are identical, understanding this 1% difference can illuminate the variances that ultimately contribute to health disparities. Currently, representation is significantly skewed, as less than 2% of genetic data derives from people of African descent. This groundbreaking project propels the charge in closing this disparity and paints an inclusive picture of human genetic diversity.

A new "reference genome" will serve as comparative models to the complete DNA sets of individuals, potentially leading to groundbreaking revelations about the unique genetic variants within African populations. These advancements could then translate into potentially life-saving discoveries in the form of new drugs and diagnostic tests.

The not-for-profit Diaspora Human Genomics Institute, an entity launched by Meharry, will handle data management. This initiative invites collaboration beyond its founding partners. The University of Zambia, as well as other historically black colleges and universities in the United States, are slated to take part. They are tasked with recruiting participants willing to donate blood, the genetic material of which will be sequenced at the Regeneron Genetics Center at no cost.

This 10-year research initiative also encompasses a plan to establish a grant program. The program is designed to support research, education in genomics, and broader STEM programs for youth.